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It is also used in the treatment of polycystic ovary syndrome. With this type of diabetes, insulin produced by the pancreas is not able to get sugar into the cells of the body where it can work properly Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. A potential drawback of using a combination medication is that it’s harder to adjust the dosage; the medications come with certain doses of one medication to the other Aug 15, 2014 · New Metformin Combo Drug Approved for Type 2 Diabetes. 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